Liu Runhui, a professor from the School of Materials Science and Engineering at East China University of Science and Technology, has achieved breakthrough results in the field of anti-adhesion and anti-implant foreign body research. Inspired by silk proteins, the researchers designed a new class of anti-adhesion and anti-implantation foreign-responsive polymer materials with simple structure, good biocompatibility and stability in vivo-poly-β-serine. Recently, the results were published in "German Applied Chemistry", and was evaluated by the reviewing experts as the top 10% of the total papers published in the journal.
Although polyethylene glycol (PEG) is widely used as an anti-adhesion material in clinical treatment, studies have shown that PEG is easily oxidatively degraded in the body, and there is an immunogenicity beyond what people generally recognize. Therefore, finding a new generation of anti-adhesion and anti-implantation foreign material reaction materials that may replace PEG is one of the core scientific issues and challenges in the field of biomaterial research.
According to reports, poly-beta-serine-modified surfaces can effectively resist the adsorption of various proteins, serum contamination, cells, platelets and various microbial adhesion; poly-beta-serine hydrogel implanted in mice did not The obvious foreign body reaction was found, which was significantly better than the PEG implanted control group with significant foreign body reaction. The researchers first proposed the hypothesis of "double hydrogen bond hydration" to explain the excellent anti-adhesion and anti-implantation foreign body reaction properties of poly-β-serine, and this was verified by computational simulation.
Experts said that this new type of anti-adhesion and anti-implant foreign body reaction polymer materials is expected to be used to solve the common clinical problems of implant material foreign body reaction, and has a wide range of related fields in implant materials and devices, drug delivery, etc. Application prospects. (Reporter Huang Xin correspondent Cai Liao)
Ring magnets are permanent magnets that are distinguished by their shape: they are round with a hole in the middle, and because of this shape they are sometimes referred to as donut magnets.
Ring magnets are most commonly used in science experiments, although they also have medical applications. Some people have implantable cardioverter-defibrillators, or ICDs, that automatically apply shocks to their hearts if the rhythm develops irregularities. If the devices malfunction, they can shock the patients unnecessarily, leading to irregular rhythms and possibly death. Medical personnel sometimes place these magnets on patients` chests over the ICDs to disable the devices.
Ring magnets are similar to discs, but feature a hole in the centre. The reduced volume of the magnet results in less strength, but increases their versatility - rings slide easily onto tubes or rods. Rare Earth rings are available in sizes from 6mm outer diameter up to 120mm, and with a variety of internal diameters and thicknesses.
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